Early in his medical practice, Dr F. Cornud was involved in vascular and non-vascular interventional radiology, while making the choice of diagnostic and interventional uro-radiology sub-specialization.

• As early as 1987, he started to use high frequency transrectal ultrasonography (TRUS) probes, and was the first user in France of the first biopty gun to perform TRUS-guided biopsies.
• In 1992, he promoted endorectal prostate MRI at Necker Hospital. Since, Dr Cornud is fully involved in prostate MRI and was from 2012 to 2018 the chief of the diffusion weighted imaging section of the steering PI-RADS committee.
• Since 2011, Dr Cornud is also involved in MRI-TRUS image fusion with different software-based systems. He switched in 2019 to the ultra-high frequency (29 MHz) TRUS probe, (micro ultrasound or microUS, Exact Imaging, Canada) to evaluate how tumor foci of prostate cancer detected on MRI could be visualized without the computation constraints of software-based image fusion systems.
• Due to the high accuracy of post-MRI microUS, Dr Cornud has launched, with Dr Galiano, Urologist at Clinique de l’Alma, a study on focal laser ablation of PCa. MRI-directed microUS is used to transperineally insert laser fibers within the tumor and proceed to a thermal tumor ablation monitored in real time under real time microUS guidance. Data of the treated patients are collected in an European registry.
• Since 2020, Dr CORNUD has also been evaluating the efficacy of interstitial laser fiber thermal ablation of benign prostatic hyperplasia (BPH). The fibers are transperineally inserted within the BPH tissue. The delivered laser energy enables a separate thermal ablation of each prostate lobe, sparing the bladder neck and proximal uretra, resulting in a decrease of prostate volume by 45-50%. and a substantial improvement of miction disorders. Medical treatment (alpha-blockers) can be discarded. The midline being respected, this minimally invasive treatment avoids the occurrence of retrograde ejaculation.